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Mucin type O-glycan biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
UDP-N-acetyl-D-glucosamine + glycoprotein_N-acetyl-D-galactosamine <=> N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-alpha-D-galactosaminyl-R + H+ + UDP 2.4.1.147 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase

CMP-N-acetylneuraminate + beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R <=> CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R 2.4.99.4 beta-galactoside alpha-2,3-sialyltransferase

UDP-galactose + beta-D-GlcNAc-(1->6)-alpha-D-GalNAc-1-Ser/Thr <=> UDP + beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)-alpha-D-GalNAc-1-Ser/Thr 2.4.1

UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-galactosaminyl-R <=> UDP + beta-D-GlcNAc-(1->6)-alpha-D-GalNAc-1-Ser/Thr 2.4.1.102 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase
2.4.1.148 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase


UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R <=> UDP + beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R 2.4.1.102 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase
2.4.1.146 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase


UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-alpha-D-galactosaminyl-R <=> N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-D-galactosaminyl-R + H+ + UDP 2.4.1.102 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase
2.4.1.148 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase


CMP-N-acetylneuraminate + glycoprotein_N-acetyl-D-galactosamine <=> Sialyl-Tn_antigen + CMP + H+ 2.4.99.3 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase

CMP-N-acetylneuraminate + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-alpha-D-GalNAc-1-Ser/Thr <=> CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-alpha-D-GalNAc-1-Ser/Thr 2.4.99.3 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase

UDP-N-acetyl-D-galactosamine + protein <=> UDP + N-acetyl-beta-D-galactosaminyl-R 2.4.1.41 polypeptide N-acetylgalactosaminyltransferase

UDP-galactose + glycoprotein_N-acetyl-D-galactosamine <=> beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R + UDP + H+ 2.4.1.122 N-acetylgalactosaminide beta-1,3-galactosyltransferase

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